Assessment of ultrasound field properties and the potential effects on cells

Ultrasound is regarded a convenient and safe tool to acquire diagnostic information that we need for clinical use. For a long time ul trasound has been counted as a harmless method, but after all, there is a heating and a mechanical impact by ul trasound exposure. This influence can reveal both posi tive (e .g., cell plant growth) and negative (e.g. cell death) effects. Acoustic exposure pattern changed drastically in recent years due to the rapid, technological developments in ul trasound imaging. Ultrasound imaging has become more sophisticated and new techniques are becoming more common, bringing with them not only increased diagnostic capabilities , but also potential threats as far as safety considerations are concerned. The goal of the thesis project is to analyze the ul trasound field characteris tics, based on which research would be achievable in the future about how cells are affected by ul trasound exposure with different basic parameters. These parameters include exci tation pressure amplitude, number of cycles in a pulse (n), pulse repeti tion frequency (PRF), acoustic working frequency (f), phase of ul trasound, shape of ul trasound wave (window mode). Some pilot cell experiments are also done in this